Burden and Clinical Manifestations
- PDP is an important complication of Parkinson’s disease that accompanies progressive motor and nonmotor symptoms (Figure 1)1
- This nonmotor complication of Parkinson’s disease affects an estimated 30% to 60% of the roughly 1 million patients in the United States with Parkinson’s disease1-3
- Manifestations of PDP may include hallucinations, including hallucinations of a nonvisual character that may be auditory, tactile, gustatory, or visceral in nature3-5
- PDP is also characterized by delusions, which is a form of disordered thinking that involves firmly held beliefs not based in reality3-5
- The features of PDP are based in the neurochemistry of Parkinson’s disease6
Figure 1: Progression of Parkinson’s Disease and the Development of Parkinson’s Disease Psychosis1