Levodopa is the most common treatment used to manage Parkinson’s symptoms, such as tremor, stiffness, and slowness of movement. However, higher doses of levodopa are associated with increased risk of motor and non-motor symptoms.
Dopamine agonists directly stimulate dopamine receptors. When taken alongside levodopa, they lower the required dose of levodopa and minimize the likelihood of OFF episodes and dyskinesia.
Enzyme catechol-O-methyl transferase, or COMT. Drugs that inhibit COMT increase the bioavailability and elimination half-life of levodopa, thereby decreasing OFF episodes through.
An Introduction to Diabetic Retinopathy
The PD Thrive website and application are designed to offer practical, valuable, and unbiased information covering several facets of Parkinson’s disease, including epidemiology and pathophysiology, and a detailed review of current data on the safety, efficacy, and use of medical therapy for PD. This multicomponent program features both live and online activities for providers and their patients. Our objectives for the program are to educate clinicians and patients so they can:
- Describe the difficult-to-treat symptoms associated with advanced PD
- Review the mechanisms of action and clinical profiles of interventional therapeutic approaches for PD
- Discuss the impact of approved and investigational agents on response rates and quality of life
- Explore the challenges of evaluating current data
- Discuss how to individualize therapies
- Discuss the benefits of a multidisciplinary team-based approach to the management of patients with PD
- Explore methods for enhancing communication between health care providers and patients to empower patients in their own health care
- Evaluate challenges associated with Parkinson’s disease psychosis (PDP)
- Evaluate clinical data associated with treatment options for PDP, including efficacy and safety data
By providing useful information about existing and emerging therapeutic options, we hope to provide a beneficial learning environment for our learners, with the ultimate goal of improving care for each individual patient.